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Table 5 Diagnostic ability of RA, FA, and MD in the prediction of MS in comparison to mimics

From: Diffusion tensor imaging and voxel-based morphometry in differentiating multiple sclerosis and its mimics

Indices

Diagnostic criteria

RA

FA

MD

AUC

0.501

0.502

0.845

Cut off

 ≤ 0.232

 > 0.154

 > 1.058*

Accuracy

61.0%

67.0%

82.5%

Sensitivity, %

80.7%

96.8%

87.1%

Specificity, %

40.7%

37.0%

77.8%

PPV, %

61.0%

63.8%

81.8%

NPP, %

64.7%

90.9%

84.0%

P value

0.994

0.978

 < 0.001

  1. Bold font indicates high statistical significance
  2. PPV positive predictive value, NPV negative predictive value, AUC area under the curve, RA relative anisotropy, FA fractional anisotropy, MD mean diffusivity, MS multiple sclerosis
  3. *MD is presented in units of 10−3 mm2/s