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Table 2 The significance of maternal risk factors for fetal malformation

From: Two-dimensional and four-dimensional ultrasound in the diagnosis of non-cardiac fetal congenital anomalies in high risk pregnancies: a comparative study

Risk factors

Normal fetal group

(N = 75)

Malformed fetus

(N = 25)

χ2

P

Age of mother

  

0.851

FEP = 0.460

 < 35

68 (90.7%)

21 (84.0%)

  

 ≥ 35

7 (9.3%)

4 (16.0%)

  

Consanguinity

  

7.125*

0.008*

 Yes

47 (62.7%)

8 (32.0%)

  

 No

28 (37.3%)

17 (68.0%)

  

Past history or family history of congenital anomalies

  

6.077*

0.017*

 Yes

36 (48.0%)

5 (20.0%)

  

 No

39 (52.0%)

20 (80.0%)

  

History of medication during pregnancy

  

3.922*

0.048*

 Yes

55 (73.3%)

13 (52.0%)

  

 No

20 (26.7%)

12 (48.0%)

  

History of diabetes

  

4.476*

0.037*

 Yes

18 (24.0%)

9 (36.0%)

  

 No

57 (76.0%)

16 (64.0%)

  

History of hypertension

  

0.014

0.906

 Yes

46 (61.3%)

15 (60.0%)

  

 No

29 (38.7%)

10 (40.0%)

  
  1. P value is a statistical significance testing, if less than 0.05, is statistically significant*
  2. χ2: Chi square test, FE: Fisher Exact
  3. P: P value for comparing between the studied groups
  4. *Statistically significant at p ≤ 0.05