Diagnostic accuracy of the different pulse sequences of multi-parametric prostate MRI in the diagnosis of prostate cancer in the peripheral and transitional zones

Egyptian Journal of Radiology and Nuclear Medicine

Table 4 Diagnostic indices of various sequences of multiparametric prostate MRI for lesions located at the transitional zone

Transitional zone		Pathology
		Benign		malignant		Sensitivity	Specificity	PPV	NPV	Accuracy
		N	%	N	%
PIRADS score based on T2 sequence only (4 and 5 only as malignant)	Benign	18	100.0	7	36.8	63.16%	100.00%	100.00%	72.00%	81.08%
	Malignant	0	0.0	12	63.2
PIRADS score based on T2 sequence only (3, 4 and 5 only as malignant)	Benign	6	33.3	0	0.0	100.00%	33.33%	61.29%	100.00%	67.57%
	Malignant	12	66.7	19	100.0
PIRADS score based on diffusion sequence only (4 and 5 only as malignant)	Benign	17	94.4	10	52.6	47.37%	94.44%	90.00%	62.96%	70.27%
	Malignant	1	5.6	9	47.4
PIRADS score based on diffusion sequence only (3, 4 and 5 only as malignant)	Benign	5	27.8	1	5.3	94.74%	27.78%	58.06%	83.33%	62.16%
	Malignant	13	72.2	18	94.7
PIRADS score based on T2 and diffusion sequences only (biparametric) (4 and 5 only as malignant)	Benign	18	100.0	5	26.3	73.68%	100.00%	100.00%	78.26%	86.49%
	Malignant	0	0.0	14	73.7
PIRADS score based on T2 and diffusion sequences only (biparametric) (3, 4 and 5 only as malignant)	Benign	6	33.3	0	0.0	100.00%	33.33%	61.29%	100.00%	67.57%
	Malignant	12	66.7	19	100.0
PIRADS score based on contrast enhanced sequence only	Benign	15	83.3	10	52.6	47.37%	83.33%	75.00%	60.00%	64.86%
	Malignant	3	16.7	9	47.4
PIRADS score (multiparametric) (4 and 5 only as malignant)	Benign	18	100.0	5	26.3	73.68%	100.00%	100.00%	78.26%	86.49%
	Malignant	0	0.0	14	73.7
PIRADS score (multiparametric) (3, 4 and 5 only as malignant)	Benign	6	33.3	0	0.0	100.00%	33.33%	61.29%	100.00%	67.57%
	malignant	12	66.7	19	100.0