A proposed inclusion of magnetic resonance imaging features to the VI RADS to enhance its accuracy in predicting muscle invasion

Egyptian Journal of Radiology and Nuclear Medicine

Table 2 Numeric variables showing statistically significant differences between NMIBC and MIBC

Numeric variables	State of muscle invasion		U	p
Numeric variables	NMI (n = 41)	MI (n = 39)	U	p
Index tumor volume (cm³)	2.15 ± 1.22	2.60 ± 1.33	579.0	0.034
ADC values (× 10⁻³mm²/s)
Mean ADC for 3 ROIs	0.87 ± 0.16	0.71 ± 0.12	350	< 0.001*
Mean ADC for whole tumor volume	0.93 ± 0.15	0.75 ± 0.13	268	< 0.001*
Minimum ADC by a selected ROI	0.67 ± 0.17	0.48 ± 0.10	229	< 0.001*
Minimum ADC for whole tumor volume	0.48 ± 0.26	0.22 ± 0.16	324	< 0.001*

NMI non-muscle invasive, MI muscle invasive, ADC apparent diffusion coefficient, U Mann–Whitney test, *p value: statistically significant at < 0.05