Glioma grading using an optimized T1-weighted dynamic contrast-enhanced magnetic resonance imaging paradigm

Egyptian Journal of Radiology and Nuclear Medicine

Table 2 The levels of statistical significance for the cerebral hemodynamic (rCBV and rCBF), permeability (Ktrans, Kep, etc.), and semi-quantitative (IAUC60, Peak, etc.) indices between different grades of gliomas

	GII versus GIII	GII versus GIV	GIII versus GIV	LGG versus HGG
rCBV	0.001	< 0.001	0.004	< 0.001
rCBF	0.027	0.002	0.014	< 0.001
Ktrans (mL/g min)	0.005	< 0.001	0.004	< 0.001
Kep (1/min)	0.040	0.002	0.017	0.001
Vp (mL/g)	0.047	< 0.001	0.001	< 0.001
Ve (mL/g)	0.121	< 0.001	0.070	0.001
IAUC₆₀ (mmol Sec /L)	0.006	< 0.001	0.001	< 0.001
Wash-in rate (mmol/L Sec)	0.005	< 0.001	0.013	< 0.001
Peak (mmol/L)	0.007	< 0.001	0.006	< 0.001