Glioma grading using an optimized T1-weighted dynamic contrast-enhanced magnetic resonance imaging paradigm

Egyptian Journal of Radiology and Nuclear Medicine

Table 3 The accuracy, sensitivity, specificity, PPV, NPV, and Kappa coefficient of cerebral hemodynamic (rCBV and rCBF) indices for differentiation between the different grades of gliomas

		Threshold	Accuracy (%)	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Kappa Coeff
rCBV	GII versus GIII	2.22	76.92	70	81.25	70	81.25	0.76
	GII versus GIV	3.22	96	100	93.75	90	100	0.96
	GIII versus GIV	4.19	78.95	77.78	80	77.78	80	0.78
	LGG versus HGG	2.80	82.86	84.21	81.25	84.21	81.25	0.82
rCBF	GII versus GIII	2.10	73.08	70	75	63.64	80	0.71
	GII versus GIV	2.53	92	100	87.5	81.82	100	0.92
	GIII versus GIV	2.68	84.21	100	70	75	100	0.83
	LGG versus HGG	2.11	80	84.21	75	80	80	0.79

The discriminative thresholds of cerebral hemodynamic indices were also listed in the first column