Table 2 Summary of the histopathology-proven cases of Cladophialophora bantiana cerebral phaeohyphomycosis (CBCP) in renal transplant patients
Year (ref. no) | Age/sex | Renal failure cause | Immuno-suppress-ant | The time between transplant & CBCP onset | Presenting symptoms | Site of lesion | Imaging described in the study | Other infections before or at the time of diagnosis of CBCP | Interve-ntion | Anti-fungal | Follow up done at | Follow up findings | Manage-ment | Status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1997 [18] | 35y/M | NA | NA | 9 months | HA, GTCS, vomiting | Right parietal | CT-ring enhancing lesions | No | Biopsy | Amphotericin B | NA | NA | NA | NA |
1997 [19] | 36y/F | Microscopic angiitis/crescentic nephritis | A, C, P | 20 months | HA, left arm weakness | Right fronto-parietal | CT-ring enhancing lesions | Toxoplasmosis | Biopsy | Amphotericin B, flucytosine, itraconazole | 12 months | Regression | No | Survived |
1999 [20] | 51y/M | Hypertension | A, P | 10 years | HA, GTCS, vomiting | Left parietal | T1FS C+—ring enhancing lesion | No | Excision | Amphotericin B | 3 weeks | No change | No | Survived |
2003 [21] | 61y/M | Adeno-Carcinoma of the kidney | A, C, P | 7 years | Right arm weakness | Left parietal | CT-hypodense mass | Escherichia coli | Excision | Fluconazole, dexamethasone | 1 month | Recurrence | Resection | Death |
2016 [22] | 49y/F | Crescentic glomerulone-phritis | T, M | 3 years | HA, weakness, frequent falls | Left frontal | CT-hypodense mass | No | Excision | Posaconazole | 6 months | Resolution | No | Survived |
2018 [23] | 40y/M | NA | NA | NA | HA, altered sensorium | Left frontal | CT-ring enhancing lesions | Toxoplasmosis | Biopsy | Amphotericin B, Flucytosine, Voriconazole | 12th day | Massive bleed | No | Death |
2020 [24] | 65y/M | NA | NA | 4 years | HA, visual loss | Left parieto-occipital | T1FS C+—ring enhancing lesion | No | Excision | Amphotericin B, Flucytosine, | NA | Recurrence | Resection | Survived |
2021 (current) | 36y/M | Diabetes, hypertension | T, P | 8 years | Fever, imbalance while walking, focal seizures | Left parietal right frontal | Detail MRI with spectroscopy and long-term follow-up imaging | Covid-19, cytomegalovirus | Excision | Voriconazole | 3rd month, 7th month, 8th month | Recurrence, progression, cerebral infarcts | Resection | Death |