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Table 2 Comparison between DM, synthetic 2D + DBT, and DM + DBT on final BI-RADS assessments by Reader 1, Reader 2 and at double reading

From: Digital breast tomosynthesis in the diagnostic settings of breast cancer patients treated by conservation therapy

 

BI-RADS category

DM

Synthetic 2D + DBT

DM + DBT

p*

p

p

Reader 1

BI-RADS 1,2

191 (46%)

273(65.8%)

271 (65.3%)

0.03

0.03

0.9

BI-RADS 3

150 (36.1%)

77 (18.6%)

76 (18.3%)

0.01

0.01

0.9

BI-RADS 4,5

74 (17.8%)

65 (15.7%)

68 (16.4%)

0.1

0.1

0.3

PPV of malignancy

50/74 (67.6%)

50/65 (76.9%)

50/68 (73.5%)

0.08

0.09

0.1

Reader 2

BI-RADS 1,2

149 (35.9%)

277 (66.7%)

266 (64.1%)

0.01

0.02

0.4

BI-RADS 3

189 (45.5%)

77 (18.6%)

91 (21.9%)

0.01

0.01

0.2

BI-RADS 4,5

77 (18.6%)

61 (14.7%)

58 (14%)

0.1

0.1

0.6

PPV of malignancy

50/77 (64.9%)

50/61 (82%)

50/58 (86.2%)

0.01

0.01

0.2

Double reading

BI-RADS 1,2

160 (38.6%)

276 (66.5%)

272 (65.5%)

0.01

0.02

0.5

BI-RADS 3

185 (44.6%)

80 (19.3%)

83 (20%)

0.01

0.01

0.5

BI-RADS 4,5

70 (16.9%)

59 (14.2%)

60 (14.4%)

0.1

0.1

0.9

PPV of malignancy

50/70 (71.4%)

50/59 (84.7%)

50/60 (83.3%)

0.03

0.04

0.2

  1. Bold value indicates significant p < 0.05
  2. *Comparison between DM and synthetic 2D + DBT
  3. ↑ Comparison between DM and DM + DBT
  4. Comparison between synthetic 2D + DBT and DM + DBT