Table 1 Demographic, serum, and DTI parameters of CKD patients and controls

Demographic

Age (years)

12.2 ± 2.7 (7–18)

11.0 ± 2.5 (6–15)

0.23

Sex (M–F)

19/16

10/9

0.16

Serum parameters

Serum creatinine (mg/dl)

1.41 ± 0.267

0.89 ± 0.22

< 0.001*

e-GFR

47.6 ± 7.12

73.2 ± 16.5

< 0.001*

Diffusion parameters

Cortex: FA

0.20 ± 0.07

0.27 ± 0.08

< 0.001*

ADC (× 10⁻³ mm²/s)

1.98 ± 0.23

1.65 ± 0.13

< 0.001*

Medulla: FA

0.18 ± 0.08

0.31 ± 0.09

< 0.001*

ADC (× 10⁻³ mm²/s)

2.03 ± 0.23

1.68 ± 0.16

< 0.001*