Table 1 Eighth edition of TNM staging of lung cancer [11]
From: The added value of18F-FDG PET/CT in staging non-small cell lung cancer
Category or stage | Descriptor | 5-year survival rate (%) |
|---|---|---|
T category | ||
TX | Tumor in sputum and/or bronchial washings, not assessed at imaging or bronchoscopy | |
T0 | No evidence of primary tumor | |
Tis | Carcinoma in situ | ... |
T1 | ≤ 3 cm in longest axis | ... |
T1a(mi) | Minimally invasive adenocarcinoma | ... |
T1a | ≤ 1 cm in the longest axis | 92 |
T1b | > 1 to ≤ 2 cm in the longest axis | 83 |
T1c | > 2 to ≤ 3 cm in the longest axis | 76 |
T2 | > 3 to ≤ 5 cm in the longest axis; involves the main bronchus, visceral pleura, or atelectasis or obstructive pneumonitis extending to the hilum | 67 |
T2a | > 3 to ≤ 4 cm in the longest axis | 67 |
T2b | > 4 to ≤ 5 cm in the longest axis | 60 |
T3 | > 5 to ≤ 7 cm in the longest axis; invades the chest wall, phrenic nerve, or parietal peri-cardium; or nodule in the same lobe as the primary tumor | 52 |
T4 | > 7 cm in the longest axis; invades the diaphragm, mediastinum, carina, trachea, heart, great vessels, recurrent laryngeal nerve, esophagus, or vertebral body; nodule in different ipsilateral lobes | 38 |
N category | ||
N0 | No regional nodal metastases | 75 |
N1 | Metastasis in ipsilateral peribronchial or hilar nodes or intrapulmonary nodes | 49 |
N2 | Metastasis in ipsilateral mediastinal nodes or subcarinal nodes | 36 |
N3 | Metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular nodes | 20 |
M category | ||
M0 | No distant metastasis | |
M1a | Tumor nodule in contralateral lung; tumor with pleural or pericardial nodules or malignant pleural or pericardial effusion | 11.4 |
M1b | Solitary single-organ extrathoracic metastasis | 11.4 |
M1c | Multiple extrathoracic metastases in one or multiple organs | 6.3 |
Stage group | ||
Stage IA1 | T1a(mi)N0 M0, T1aN0M0 | 92 |
Stage IA2 | T1bN0M0 | 83 |
Stage IA3 | T1cN0M0 | 77 |
Stage IB | T2aN0M0 | 68 |
Stage IIA | T2bN0M0 | 60 |
Stage IIB | T1aN1M0, T1bN1M0, T1cN1M0, T2aN1M0, T2bN1M0, T3N0M0 | 53 |
Stage IIIA | T1aN2M0, T1bN2M0, T1cN2M0, T2aN2M0, T2bN2M0, T3N1M0, T4 N0 M0,T4N1M0 | 36 |
Stage IIIB | T1aN3M0, T1bN3M0, T1cN3M0, T2aN3M0, T2bN3M0, T3N2M0, T4N2M0 | 26 |
Stage IIIC | T3N3M0, T4N3M0 | 13 |
Stage IVA | Any T, any N, M1a; any T, any N, M1b | 10 |
Stage IVB | Any T, any N, M1c | 0 |